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S Hino Selected Research

vesnarinone

3/2003Transcriptional activation of cyclin-dependent kinase inhibitor, p21waf1 gene by treatment with a differentiation inducing agent, vesnarinone in a human salivary gland cancer cell line.
10/2002Vesnarinone, a differentiation inducing drug, directly activates p21(waf1) gene promoter via Sp1 sites in a human salivary gland cancer cell line.
6/2000Over-expression of TSC-22 (TGF-beta stimulated clone-22) markedly enhances 5-fluorouracil-induced apoptosis in a human salivary gland cancer cell line.

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S Hino Research Topics

Disease

4Squamous Cell Carcinoma of Head and Neck
10/2015 - 07/2001
4Neoplasms (Cancer)
03/2003 - 07/2000
4Salivary Gland Neoplasms (Salivary Gland Cancer)
03/2003 - 06/2000
2Varicose Veins (Varicose Vein)
08/2004 - 10/2001
2Squamous Cell Neoplasms (Squamous Cell Cancer)
03/2003 - 11/2001
2Esophageal and Gastric Varices (Esophageal Varices)
10/2001 - 10/2001
1Lupus Nephritis
07/2014
1digital ulcers
05/2009
1Sclerosis
05/2009
1Systemic Scleroderma (Systemic Sclerosis)
05/2009
1Peripheral Vascular Diseases (Peripheral Vascular Disease)
05/2009
1Mixed Connective Tissue Disease (MCTD)
05/2009
1Pulmonary Arterial Hypertension
05/2009
1Connective Tissue Diseases (Connective Tissue Disease)
05/2009
1Dyspnea (Shortness of Breath)
05/2009
1Dermatitis
04/2009
1Osteomyelitis
07/2005
1Mouth Neoplasms (Oral Cancer)
10/2004
1Hyperplasia
10/2004
1Prostatic Neoplasms (Prostate Cancer)
03/2003
1Residual Neoplasm
11/2001
1Hemorrhage
10/2001
1Neoplasm Metastasis (Metastasis)
08/2001
1Hyperuricemia
06/2001
1Nephrocalcinosis
01/2001
1Hypercalciuria
01/2001
1Dent Disease
01/2001
1Proteinuria
01/2001
1Interstitial Nephritis (Tubulointerstitial Nephritis)
02/2000
1familial juvenile Nephronophthisis
02/2000
1Infections
01/2000
1Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
01/2000

Drug/Important Bio-Agent (IBA)

4Pharmaceutical PreparationsIBA
03/2003 - 06/2000
3vesnarinoneIBA
03/2003 - 06/2000
2Indocyanine Green (Cardio-Green)FDA LinkGeneric
10/2015 - 10/2001
2AntigensIBA
04/2009 - 02/2000
2Messenger RNA (mRNA)IBA
11/2001 - 08/2001
2Fluorouracil (Carac)FDA LinkGeneric
11/2001 - 07/2000
2DNA (Deoxyribonucleic Acid)IBA
01/2001 - 01/2000
2Complementary DNA (cDNA)IBA
07/2000 - 06/2000
1Colloids (Colloid)IBA
10/2015
1Biomarkers (Surrogate Marker)IBA
07/2014
1Bosentan (Tracleer)FDA Link
05/2009
1Endothelin Receptor AntagonistsIBA
05/2009
1Monoclonal AntibodiesIBA
04/2009
1AntibodiesIBA
04/2009
1Histones (Histone)IBA
04/2009
1Immunoglobulin E (IgE)IBA
04/2009
1Alendronate (Alendronate Sodium)FDA LinkGeneric
07/2005
1Anti-Bacterial Agents (Antibiotics)IBA
07/2005
1Insulin (Novolin)FDA Link
10/2004
1Proliferating Cell Nuclear Antigen (PCNA)IBA
10/2004
1Cyclin-Dependent Kinases (cdk Proteins)IBA
03/2003
1Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA
11/2001
1Thymidylate SynthaseIBA
11/2001
1SolutionsIBA
10/2001
1Collagen Type I (Type I Collagen)IBA
08/2001
1Proto-Oncogene Proteins c-metIBA
08/2001
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
08/2001
1AcidsIBA
07/2001
1Tretinoin (Retinoic Acid)FDA LinkGeneric
07/2001
1Bromodeoxyuridine (BrdU)IBA
06/2001
1PhytohemagglutininsIBA
06/2001
1Nonsense Codon (Nonsense Mutation)IBA
01/2001
1CLC-5 chloride channelIBA
01/2001
1Growth Hormone (Somatotropin)IBA
01/2001
1Transforming Growth Factor beta (TGF-beta)IBA
07/2000
1TinIBA
02/2000
1Proteins (Proteins, Gene)FDA Link
02/2000

Therapy/Procedure

3Therapeutics
03/2003 - 10/2001
2Ligation
10/2001 - 10/2001
2Sclerotherapy
10/2001 - 10/2001
1Neck Dissection (Radical Neck Dissection)
10/2004
1Endoscopes
08/2004
1Catheters
08/2004
1Radiotherapy
11/2001
1Lasers (Laser)
10/2001
1Semiconductor Lasers
10/2001
1Intraperitoneal Injections
07/2000